主 要 學 術(shù) 成 就 |
在中藥及其復方的活性成分研究及其體內(nèi)藥物代謝研究,、復雜樣品前處理技術(shù)等領(lǐng)域進行了持續(xù)性研究,，建立了多種中藥微量或痕量組分的萃取及篩選方法，并提出相關(guān)理論,，研究和探討了中藥活性成分在體內(nèi)外的多組分多靶點相互作用及機理,，解決了中藥的微量或痕量組分的高靈敏，高選擇和快速的定性,、定量分析等問題,。主持國家青年基金項目1項和省級自然科學基金1項，出版專著（合著）1本,，授權(quán)發(fā)明專利2項,，獲科技進步獎1項，以第一或通訊作者發(fā)表學術(shù)論文20余篇,，其中SCI收錄20余篇,，EI收錄1篇。 |
代表性論文 |
[1] Xuan Chen*, Jie Li, Yanqin Zhang, Shuang Hu, Yan Du, Xiaohong Bai. Double salting-out effect assisted heat-shrinkable tubing liquid phase microextraction followed by high performance liquid chromatography for determination of flavonoids in human plasma. Journal of Chromatography A, 2019, 1603: 44-50（IF =3.858,，醫(yī)學2區(qū)） [2] Xuan Chen*, Jie Li, Shuang Hu, Xiaohong Bai, Haodong Zhao, Yi Zhang, Fibroin/dodecanol floating solidification microextraction for the preconcentration of trace levels of flavonoids in complex matrix samples. Journal of Chromatography B, 2018, 1072: 17-24（IF =2.603,，醫(yī)學3區(qū)） [3] Xuan Chen*, Yanqin Zhang, Zhuoyi Li, Xiaohong Bai, Shuang Hu, Runqin Wang, Li Yang, Yifang Zhang, Dan Tie. Comparison and application of two microextractions based on syringe membrane filter. J. Sep. Sci., 2020, 43（2）: 462-469. （IF =2.577，醫(yī)學3區(qū)） [4] Xuan Chen, Zhuoyi Li Xin Ge Shuang Hu Runqin Wang, Li Yang, Zhihui Yu, Xiao-hong Bai*. Ballpoint connector-protected salt-oil-salt liquid phase microextraction for concentration and enrichment of trace anthraquinone compounds in rhubarb. J. Sep. Sci., 2019, 42: 2231-2238. （IF =2.516,，醫(yī)學3區(qū)） [5] Xuan Chen*, Jin Wang, Shuang Hu, Xiaohong Bai, Hollow-?ber double-solvent synergistic microextraction with high-performance liquid chromatography for the determination of antitumor alkaloids in Coptis chinensis. J. Sep. Sci. 2016, 39, 827-834.（IF =2.557,，化學 3區(qū)） |
