標(biāo)志性成果 |
主持項目 1.國家自然科學(xué)基金青年項目,,81802825,,F(xiàn)AT1通過調(diào)控Wnt/β-catenin信號通路影響食管鱗癌細(xì)胞干性的機制研究,,2019/01-2021/12,,21萬元,,結(jié)題,,主持 2.山西省自然科學(xué)研究面上項目,,202203021211226,F(xiàn)AT1通過調(diào)控Hippo信號通路逆轉(zhuǎn)食管鱗癌細(xì)胞耐藥性的機制研究,,2023/01-2025/12,10萬元,,在研,主持 3.山西省青年科技研究基金, 201701D221249, FAT1在食管鱗癌中的功能驗證及機制研究, 2017/07-2019/12, 2萬元, 結(jié)題, 主持 代表性論文 1.Xiaoling Hu, Yongping Cui*, FAT1 prevents epithelial mesenchymal transition (EMT) via MAPK/ERK signaling pathway in esophageal squamous cell cancer, Cancer Letters, 2017, 31;397:83-93. 2.Xiaoling Hu, Pengzhou Kong*, Xiaolong Cheng*, FAT1 inhibits cell migration and invasion by affecting cellular mechanical properties in esophageal squamous cell carcinoma, Oncology Reports,2018, 39(5): 2136-2146. 3.Guodong Li#, Xiaoling Hu#, Tongli Li*, Xiaohui Zhang*, C-fos upregulates P-glycoprotein, contributing to the development of multidrug resistance in HEp-2 laryngeal cancer cells with VCR-induced resistance. Cell Mol Biol Lett. 2018, 20;23:26. 4.Yuanfang Zhai, Xiaoling Hu*, Xiaolong Cheng*, FAT1 downregulation enhances stemness and cisplatin resistance in esophageal squamous cell carcinoma, Molecular and Cellular Biochemistry, 2022, 477(12):2689-2702. 學(xué)術(shù)榮譽 2018 年獲得山西省“三晉英才”優(yōu)秀青年人才稱號 |