標(biāo)志性成果 |
(請(qǐng)按提綱填寫) 1. 科研項(xiàng)目 (1)中華人民共和國(guó)科學(xué)技術(shù)部,國(guó)家重點(diǎn)研發(fā)項(xiàng)目,2019YFC1710800,高品質(zhì)道地中藥材恒山黃芪,、潞黨參,、北柴胡生態(tài)種植示范研究,2019-12至2021-12,25萬元,子課題負(fù)責(zé)人 (2)山西省教育廳,山西省“1331工程”2018年重點(diǎn)創(chuàng)新團(tuán)隊(duì)建設(shè)計(jì)劃支持培育團(tuán)隊(duì),11,黃芪活性分子作用機(jī)制與健康產(chǎn)品研發(fā)創(chuàng)新團(tuán)隊(duì),2019-01至2022-12,60萬元,主持 (3)山西省科學(xué)技術(shù)廳,面上項(xiàng)目,20210302123300,黃芪活性成分調(diào)控RIPK1程序性壞死防治全身炎癥反應(yīng)綜合征的新機(jī)制研究,2021-06至2024-06,9萬元,主持 (4)山西省教育廳,山西省高等學(xué)校科技成果轉(zhuǎn)化培育項(xiàng)目,6,高活性ACE2/Mpro雙靶點(diǎn)2019-nCoV抑制劑的快速篩選與藥物設(shè)計(jì),2020-01至2021-12,20萬元,主持 (5)山西省黃芪資源產(chǎn)業(yè)化及產(chǎn)業(yè)國(guó)際化協(xié)同創(chuàng)新中心,山西省黃芪資源產(chǎn)業(yè)化及產(chǎn)業(yè)國(guó)際化協(xié)同創(chuàng)新中心項(xiàng)目,HQXTCXZX2016-021,黃芪多糖與黃酮類成分的免疫調(diào)控作用研究,2016-06至2020-12,50萬元,主持 2.學(xué)術(shù)論文 (1)One-Pot and Sustainable Liquid-Phase Peptide Extension for Synthesis of C-terminal AmidationPeptides Aided by Small-molecular TAGs, Organic Chemistry Frontiers, 2023, 10: 6158-6165(通訊作者) (2)A pivotal role of selective autophagy in mitochondrial qualitycontrol: Implications for zinc oxide nanoparticles induced neurotoxicity, Chemico-BiologicalInteractions, 2022, 363: 110003-110003(通訊作者) (3)Selenium nanoparticles fabricated in laminarin polysaccharides solutions exert their cytotoxicities in HepG2 cells by inhibiting autophagy and promoting apoptosis, InternationalJournal of Biological Macromolecules, 2019, 137: 829-835(通訊作者) (4)Chitosan attenuates dibutyltin-induced apoptosis in PC12 cells through inhibition of themitochondria-dependent pathway, Carbohydrate Polymers, 2016, 151(no.0): 996-1005(通訊作者) 3.學(xué)術(shù)榮譽(yù) 4.科技獎(jiǎng)勵(lì) 5.發(fā)明專利 李青山;梁泰剛;苗俊秋;陳景潤(rùn);崔東曉;閆超群;韓玲革;京尼平衍生物及在制備防治神經(jīng)退行性疾病藥物中的應(yīng)用,2017-1-17,中國(guó),CN201710035833.5 6.學(xué)術(shù)任職 山西省藥學(xué)會(huì)藥物化學(xué)專業(yè)委員會(huì)主任委員 |